protein-mcp-server MCP Server
MCP Server for 3D protein structural data retrieval & analysis from RCSB PDB, PDBe, and UniProt.
Publisher claimed. No tool list reported, and Pod has not connected to this server.
Status
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Connect
Published as protein-mcp-server on npm. Runs locally.
Known issues
54 problems reported by people outside the maintainer team. Issues filed by the project's own owners, members and collaborators are excluded — those are release checklists and internal refactors, not things that will go wrong for you. Showing 12.
Most discussed
feat(search): add retrieval for bounded RCSB result sets
Use case
protein_search_structures, protein_find_similar with by: "sequence", and protein_track_ligands with mode: "structures_with_ligand" expose totalCount but accept only limit. A caller cannot request a later RCSB page without leaving the server.
Proposed behavior
Add an optional start input to those three RCSB-backed result modes. start is a zero-based result offset, defaults to 0, and combines with the existing limit (1–100). The name matches RCSB Search AP
Read the thread · 2026-08-17 · closed · 2 comments
feat(protein_analyze_collection): disclose combined cross-tab bucket size
Use case
protein_analyze_collection applies the same bucket_limit cap independently to the parent dimension and to the nested cross-tab child, so a two-dimension group_by can return up to cap² buckets. At the default cap of 50 that is up to 2,500 buckets in one response; at the maximum it is larger still.
Each position honestly discloses its own truncation — the parent dimension carries truncated, and so does each child — so nothing is hidden from a caller who inspects every leve
Read the thread · 2026-08-17 · closed · 2 comments
bug(protein_analyze_collection): group_by accepts the same dimension twice
Server version
0.4.2
mcp-ts-core version
^0.11.5
Runtime
Bun
Runtime version
Bun 1.3.14
Transport
HTTP (Streamable HTTP)
OS
macOS 26.1
Description
protein_analyze_collection accepts the same dimension twice in group_by. {"group_by": ["method", "method"]} passes schema validation and reaches buildFacetSpec('method', interval, 'method'), which builds a method facet nested inside itself and sends that to RCSB.
Verified live against RCSB, the self-ne
Read the thread · 2026-08-16 · closed · 2 comments
feat(facets): nested cross-tab child is single-valued, not an array
Use case
The facet output schema advertises buckets[].children as an unbounded array of nested dimensions, but no code path can produce more than one element. Three independent bounds enforce that:
FacetSpec.child(src/services/rcsb/rcsb-service.ts) is a single optional spec, not a list.toRcsbFacetrequests exactly one nested facet:if (spec.child) facet.facets = [toRcsbFacet(spec.child)].normalizeBucketsreads only index 0 of the upstream response and wraps the result
Read the thread · 2026-08-16 · closed · 2 comments
enhancement(protein_track_ligands): structures_with_ligand score is a constant; sort is undocumented
protein_track_ligands mode structures_with_ligand returns a score on every entry that carries no signal, and an ordering that isn't stated.
Observed
{ mode: "structures_with_ligand", comp_id: "HEM", limit: 8 } → every row scores 1.00, ordered by PDB ID ascending (101M, 102M, 103M … — myoglobins ahead of any hemoglobin). Containment is boolean (an entry either has the component or doesn't), so RCSB's relevance score is uniform and the column is noise; the PDB-ascending order is
Read the thread · 2026-07-03 · closed · 2 comments
Most recent
bug(protein_search_structures): sequence-only controls are silently ignored
Server version
0.5.3
mcp-ts-core version
^0.12.3
Runtime
Bun
Runtime version
Bun 1.4.0 / Node v26.5.0
Transport
HTTP (Streamable HTTP)
OS
macOS 26.1
Description
protein_search_structures accepts min_identity and max_evalue without sequence, then silently runs the non-sequence query. A malformed workflow therefore looks filtered even though neither threshold affects the result.
Steps to reproduce
- Call
protein_search_structureswith `{ "q
Read the thread · 2026-08-31 · open · 0 comments
bug(protein_analyze_collection): zero-match scopes omit the declared notice
Server version
0.5.3
mcp-ts-core version
^0.12.3
Runtime
Bun
Runtime version
Bun 1.4.0 / Node v26.5.0
Transport
HTTP (Streamable HTTP)
OS
macOS 26.1
Description
protein_analyze_collection returns an empty success for a zero-match scope without the empty-scope advisory declared by its enrichment contract. The result is technically distinguishable through total: 0, but it gives no recovery guidance.
Steps to reproduce
- Call `protein_analyze_coll
Read the thread · 2026-08-31 · open · 0 comments
docs(tools): make catalog descriptions caller-facing
The MCP catalog mixes user-facing contracts with implementation mechanics and audience assumptions. Examples include protein_analyze_collection describing a single upstream call and "no row pull," protein_compare_structures describing its internal fanout/concurrency cap, and an output field saying it lets "an agent" cite a structure.
Related: #38
Proposal
Keep provider identity, limits, partial-success behavior, and resume semantics. Remove API-call counts, internal routing/fanout deta
Read the thread · 2026-08-31 · open · 0 comments
bug(protein_find_similar): completed Foldseek results have no retrieval path
Server version
0.5.3
mcp-ts-core version
^0.12.3
Runtime
Bun
Runtime version
Bun 1.4.0 / Node v26.5.0
Transport
HTTP (Streamable HTTP)
OS
macOS 26.1
Description
protein_find_similar silently slices completed Foldseek results to limit. The response has no total, truncation flag, offset, or reusable completed-job ticket, so hits beyond that cap cannot be retrieved through the server.
Related: #41
Steps to reproduce
- Call
protein_find_similar
Read the thread · 2026-08-31 · open · 0 comments
bug(protein_search_structures): truncated facets omit recovery guidance
Server version
0.5.3
mcp-ts-core version
^0.12.3
Runtime
Bun
Runtime version
Bun 1.4.0 / Node v26.5.0
Transport
HTTP (Streamable HTTP)
OS
macOS 26.1
Description
protein_search_structures marks a capped facet as truncated: true, but its enrichment omits the promised truncation advisory and gives no route to the remaining buckets.
Related: #13, #41
Steps to reproduce
- Call
protein_search_structureswith `{ "query": "kinase", "facets": ["organ
Read the thread · 2026-08-31 · open · 0 comments
bug(protein_analyze_collection): interval is silently ignored for incompatible dimensions
Server version
0.5.3
mcp-ts-core version
^0.12.3
Runtime
Bun
Runtime version
Bun 1.4.0 / Node v26.5.0
Transport
HTTP (Streamable HTTP)
OS
macOS 26.1
Description
protein_analyze_collection.interval is accepted for every group_by shape, but it only reaches the top-level facet when that facet is a histogram. A terms-only call silently drops it, and a numeric/date child in a cross-tab keeps its default interval.
Related: #15
Steps to reproduce
- C
Read the thread · 2026-08-31 · open · 0 comments
bug(protein_track_ligands): formula queries run as name searches
Server version
0.5.3
mcp-ts-core version
^0.12.3
Runtime
Bun
Runtime version
Bun 1.4.0 / Node v26.5.0
Transport
HTTP (Streamable HTTP)
OS
macOS 26.1
Description
protein_track_ligands advertises find_ligand.query as a chemical name or formula, but formula input is handled as a name search. A caller can receive chemically unrelated component IDs with no indication that the declared formula path was not applied.
Related: #17
Steps to reproduce
Read the thread · 2026-08-31 · open · 0 comments
See all 23 reports Pod holds for protein-mcp-server — of 54 qualified upstream.
Firsthand observations
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For agents
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